Reflux Image BlankAcid Medicine SymptomGerd Image Medicine
 

Home | About us | Site Map | Link Partners

reflux guide

 
 

Treatment Of Gerd
By Jack Smith
Life style changes
Several changes in lifestyle, related to individuals’ habits are recommended.

As mentioned before, reflux is more troublesome at night when the individual is lying down. Relief can be provided by elevating the patient’s upper body at night. This can be done by putting blocks under the bed’s feet on the head side. Also, reflux has been observed to occur less frequently when the patient lies on his left side rather than on the right.

Alterations in eating habits are also recommended. Certain foods aggravate reflux. These should be religiously avoided. Chocolate, alcohol, caffeinated drinks, peppermint, fatty foods, spicy foods, citrus juices, carbonated drinks and tomato juice fall in this category. Smoking should be completely stopped.

Reflux is more after meals when the stomach is distended with food. Hence, smaller and earlier evening meals are recommended. A smaller meal distends the stomach less and an earlier evening meal would mean that by bedtime, it has been digested and the stomach is empty. Therefore, reflux will be less bothersome when the patient lies down.

Antacids
Antacids are the chief form of treatments for patients of GERD. They neutralize the acid in the stomach, thus leaving no acid to reflux. However, their effect is brief as they empty out of the stomach quickly and subsequently, acid accumulates once again. An antacid, if taken one hour before a meal and then again taken approximately two hours after it, is most effective in reducing reflux.

Histamine antagonists
As mentioned above, antacids are effective for a very short duration. Hence, histamine antagonists were developed as a more long lasting remedy for treatment of acid-related diseases, including GERD. The chemical Histamine produces acid in the stomach. Histamine antagonists prevent histamine from doing its work.

Histamine produces acid, particularly after a meal. Therefore, histamine antagonists are best taken 30 minutes before a meal so that they at the peak of efficiency when most of the acid is being produced.

Proton pump inhibitors
A proton

pump inhibitor or PPI was another type of drug developed for acid-related diseases such as GERD. Like the histamine antagonists, a PPI also blocks off the production of acid in the stomach. Moreover, it does so for a longer duration than the histamine antagonist. Also, unlike the histamine antagonist, the PPI protects the esophagus from acid, allowing for esophageal inflammation to heal. PPI’s are used when histamine antagonists are found to be inadequate.

Pro-motility drugs
Pro-motility drugs stimulate the muscles of the gastro intestinal tract. These include the esophagus, stomach, small intestine and/or colon. They heighten the pressure in the LES and boost the wave-like contractions of the esophagus. Both these effects reduce acid reflux.

Surgery
Surgery is very effective in relieving the symptoms of GERD and is resorted to when other means have proved to be inadequate. The surgical procedure that is undertaken to prevent reflux is known as fundoplication.

Endoscopy
In recent times, endoscopic treatments have been applied to deal with GERD. In the first type of treatment, the LES area is stitched, which tightens the muscle. In the second type of treatment, radio frequency waves are applied just above the LES. They cause a scar to form below the esophageal lining. When this scar shrinks, it pulls the surrounding tissue, thus tightening the LES area. There is yet another type of endoscopic treatment in which material is injected into the esophageal wall, in the LES area. This raises the pressure on the LES, thus preventing reflux.

Jack Smith writes about various GERD, acid reflux disease, and health topics. This article is free to re-print as long as nothing is changed, all links remained intacked, the bio remains in full and the rel="nofollow" tag is not added to any of the links. Thank-you Please Visit Beat Acid Reflux for more information and resources.


 
 
  Here are some articles to start with..  
 
 
The Best Natural Cure For Acid Reflux
By Kerry
The symptoms of acid reflux in both adults as well as children are very uncomfortable to say the very least. The affliction is usually associated with the terrible painful burning sensation that Read more...
How To Treat An Acid Reflux Disease Symptom
Night after night you try to fall asleep, only to experience a painful acid reflux disease symptom. You get up, walk around, but the pain persists. What can you do to get relief?Talk to Your Read more...
 
 
Anti-Hypertensive Drugs To Enhance Esophageal Contraction
Nifedipine, a calcium-channel blocker, was shown to decrease lower esophageal sphincter pressure and increase esophageal acid exposure time, while atenolol, a b1 blocker, was shown to inhibit relaxation of the smooth muscle of the esophagus...
New Endoscopic Treatment May Spare Barrett's Esophagus Patients From Surgery
Early tumor formation in Barrett's esophagus (BE) can be effectively and safely treated with radiofrequency ablation (RFA), in combination with prior endoscopic removal of visible lesions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute...
Shape Of Barrett's Epithelium Effects Prevalence Of Erosive Esophagitis
Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus. A research team from Yokohama City University School of Medicine hypothesized that some macroscopic features of Barrett's epithelium might be useful for identifying a subgroup with a high risk for the development of esophageal adenocarcinoma...
New Hope For Therapy In Heartburn-Related Cancer
Cancer of the gullet, or oesophagus, is one of the ten most common cancers in the Western world, and there have been recent alarming increases in the number of cases each year in the US and UK. There is no good treatment, and sufferers frequently face a short, painful battle which ends all too quickly in death. Many of the cancers diagnosed are in people with a long history of heartburn...
Development Of ADX10059 Ended For Long-Term Use
Addex Pharmaceuticals (SWISS: ADXN) announced that based on preliminary review of the unblinded data from study 206, it has terminated development of ADX10059 for chronic indications, including long term treatment of gastroesophageal reflux disease and migraine prophylaxis...
Amneal Receives FDA Approval For Nizatidine Oral Solution, The First Generic Oral Solution For Axid(R) In The Market
Amneal Pharmaceuticals is pleased to announce that it has received U.S. FDA approval to manufacture Nizatidine Oral Solution in the 15 mg/mL strength effective November 18, 2009. It is an AA-rated, therapeutically equivalent alternative to Axid® Oral Solution (a licensed trademark of Braintree Labs)...
Are Manometric Findings Different Between Patients With Erosive And Nonerosive Disease?
Gastroesophageal reflux disease (GERD) is defined as the pathological retrograde movement of gastric contents into the esophagus. Various esophageal motility disturbances which may be important in reflux are observed in patients with GERD. The main esophageal motility disorder in these patients is ineffective esophageal motility (IEM)...
Why Does Percutaneous Endoscopic Gastrostomy Fail To Eliminate Gastroesophageal Reflux?
Gastroesophageal reflux (GER) is a common problem in mechanically ventilated patients and contributes to the development of esophageal mucosal injury and even erosive esophagitis. The relationship between percutaneous endoscopic gastrostomy (PEG) and subsequent development of GER is complex and not well understood...
Strengthening Sphincters In Animals Via Muscle Cell Infusion
A new study shows that muscle cells grown in the lab can restore an intestine's ability to squeeze shut properly. The work, performed in dogs and rats, might ultimately help treat patients with conditions such as gastric reflux and fecal incontinence. This technique may be used to strengthen sphincters, which are the bands of muscle that separate the major sections of your intestinal tract...
FDA Approves ZEGERID OTC(TM) For Over-the-Counter Treatment Of Frequent Heartburn
Merck & Co., Inc. announced that the U.S. Food and Drug Administration (FDA) has approved ZEGERID OTC(TM) (omeprazole 20 mg/sodium bicarbonate 1100 mg capsules), for over-the-counter treatment of frequent heartburn. ZEGERID OTC will be marketed over-the-counter by Schering-Plough HealthCare Products, Inc., the consumer healthcare division of Merck & Co., Inc...
News From The November Issue Of GIE: Gastrointestinal Endoscopy
"Screening for Barrett's esophagus in asymptomatic women" Barrett's esophagus is a condition where the lining of the esophagus changes due to chronic inflammation, generally from gastroesophageal reflux disease (GERD). Barrett's esophagus is important to recognize as it may increase the risk of developing esophageal cancer...
Reflux Esophagitis Due To Immune Reaction, Not Acute Acid Burn
Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study. Rather, gastroesophageal reflux spurs the esophageal cells to release chemicals called cytokines, which attract inflammatory cells to the esophagus...
Addex ADX10059 Monotherapy Is Effective On GERD Symptoms In Phase IIb Clinical Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced that it achieved statistically significant efficacy on the primary endpoint, increasing the number of symptom free days in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mylan Receives FDA Approval For Generic Version Of Prevacid® Through Its Subsidiary Matrix Laboratories
Mylan Inc. (NASDAQ: MYL) announced that its privately held Indian subsidiary, Matrix Laboratories Limited, has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Lansoprazole Delayed-release (DR) Capsules, 15 mg and 30 mg. This product is shipping immediately and will be sold under the Mylan Pharmaceuticals brand...
Open Wide: Incisionless Surgery To Treat GERD
Every day, more than 20 percent of the U.S. population experiences the painful burning symptoms of gastroesophageal reflux disease (GERD). For these 20 million Americans, the first line of defense is medication...
FDA Approves New Salix Product Exclusively In Catalent's Zydis(R) Fast Dissolve Technology
Catalent Pharma Solutions, one of the leading advanced drug delivery technology providers to the pharmaceutical industry, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Metozolv™ ODT (orally disintegrating tablets) metoclopramide HCL utilizing Catalent's Zydis® fast dissolve technology...
Unexpected Consequences Of Proton Pump Inhibitor Use In Reflux Disease
Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these effects and prescribe these medications carefully, according to a new commentary published in the November 2009 issue of Otolaryngology -Head and Neck Surgery...
New Procedure For Acid Reflux/GERD
Boston Medical Center (BMC) surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD. Using the new procedure known as EsophyX TIF (Transoral Incisionless Fundaplication), surgeons can repair or reconstruct the valve between the esophagus and stomach, effectively stopping GERD...
New Studies Explore Connection Between High Stress And High Exposure Jobs And GI Disorders
In two new studies, presented at the American College of Gastroenterology's (ACG) 74th Annual Scientific meeting in San Diego, researchers explored the connection between high stress, high exposure occupations and long-term gastrointestinal disorders...
New Study Results Analyzed The Use Of KAPIDEX(TM) (dexlansoprazole) For Nighttime Heartburn In Adults With Non-Erosive GERD
New data being presented at the American College of Gastroenterology (ACG) 2009 Annual Scientific Meeting in San Diego showed that treatment with KAPIDEX(TM) (dexlansoprazole) delayed release capsules over a four-week period resulted in a statistically significant greater percentage of nights without heartburn in subjects with non-erosive gastroesophageal reflux disease (GERD),...
Possible Weight-Gain From Long-Term Treatment With Proton Pump Inhibitor
Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all grades of GERD, making these agents the mainstay of treatment...
XenoPort Announces Initiation Of A Phase 2b Clinical Trial Of Arbaclofen Placarbil In Patients With Gastroesophageal Reflux Disease
XenoPort, Inc. (Nasdaq:XNPT) announced today that it has initiated a Phase 2b clinical trial of arbaclofen placarbil (AP), also known as XP19986, in patients with gastroesophageal reflux disease (GERD) who remain symptomatic despite treatment with a proton pump inhibitor (PPI)...
Heartburn Drugs Deemed Safe For Fetuses According To Ben-Gurion University Researchers
H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev...
Addex Completes Enrollment Of First Mid-Stage Clinical GERD Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced the completion of enrollment in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mayo Clinic Researchers Lead National Clinical Trial Testing New Treatment For Chronic, Severe Indigestion
Could medicines used for depression also treat chronic, severe indigestion? Scientists at Mayo Clinic suspect they can and, backed by funding from the National Institutes of Health (NIH), they are testing that premise in a nationwide clinical trial...
 
 
 
Google
Links to Page